Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | CTSS | P25774 | 15/20 | 0.53 |
| ▸ | CTSL | P07711 | 11/20 | 0.51 |
| ▸ | CTSK | P43235 | 10/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842964 | 0.85 | CTSS (0.68) | ABL1KCNH2CTSSCTSLCTSK | |
| SCHEMBL5842968 | 0.85 | CTSS (0.68) | ABL1KCNH2CTSSCTSLCTSK | |
| SCHEMBL6686940 | 0.79 | CTSS (0.56) | CTSSCTSLCTSKEPHX2 | |
| SCHEMBL6685498 | 0.79 | CTSS (0.51) | CTSSCTSLCTSKEPHX2 | |
| SCHEMBL6687608 | 0.78 | CTSS (0.50) | CTSSCTSLCTSK | |
| SCHEMBL6685630 | 0.78 | NPC1 (0.51) | CTSSCTSLCTSKSMN1; SMN2EPHX2 | |
| SCHEMBL6689357 | 0.77 | CTSS (0.50) | CTSSCTSLCTSKSMN1; SMN2EPHX2 | |
| SCHEMBL6685947 | 0.77 | CTSS (0.61) | CTSSCTSLCTSK | |
| SCHEMBL6694172 | 0.76 | CTSS (0.47) | CTSSCTSLCTSK | |
| SCHEMBL6690860 | 0.76 | CTSS (0.61) | ABL1KCNH2CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |