Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 4/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692315 | 0.84 | CNR1 (0.39) | KDM1AGPR119RORCF2RL1HDAC2 | |
| SCHEMBL5224912 | 0.81 | KDM1A (0.42) | KDM1AGPR119RORCF2RL1HDAC2 | |
| SCHEMBL6697164 | 0.79 | KDM1A (0.43) | KDM1AGPR119RORCF2RL1HDAC2 | |
| SCHEMBL5229477 | 0.79 | GPR119 (0.42) | KDM1AGPR119RORCF2RL1HDAC2 | |
| SCHEMBL6698251 | 0.78 | KDM1A (0.39) | KDM1AGPR119RORCF2RL1HDAC2 | |
| SCHEMBL6694182 | 0.78 | KDM1A (0.44) | KDM1AGPR119RORCF2RL1HDAC2 | |
| SCHEMBL6691130 | 0.77 | DNMT3A (0.41) | KDM1AGPR119RORCF2RL1HDAC2 | |
| SCHEMBL6699145 | 0.77 | ACHE (0.42) | GPR119RORC | |
| SCHEMBL6705735 | 0.76 | GHSR (0.42) | P2RX7 | |
| SCHEMBL6689376 | 0.74 | GHSR (0.53) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002802-B1 | Dipeptide derivatives as growth hormone secretagogues | PFIZER PROD INC (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6194578-B1 | GROWTH HORMONE SECRETAGOGUES; USEFUL FOR PROPHYLAXIS AND THERAPY OF OSTEOPOROSIS AND/OR FRAILTY, INSULIN RESISTANCE IN MAMMALS, CONGESTIVE HEART FAILURE, OBESITY, ACCELERATING BONE FRACTURE REPAIR REDUCING CACHEXIA AND PROTEIN LOSS | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-1002802-A1 | Dipeptide derivatives as growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-05-24 | — | — | EP | disclosed |