Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694094 | 0.92 | PTPRZ1 (0.52) | PTPRZ1SCN9AMAOBMAOA | |
| SCHEMBL6691341 | 0.81 | PTPRZ1 (0.53) | PTPRZ1SCN9AMAOBMAOA | |
| SCHEMBL6685877 | 0.79 | MAOB (0.61) | PTPRZ1SCN9AMAOBMAOA | |
| SCHEMBL6685873 | 0.79 | MAOB (0.61) | PTPRZ1SCN9AMAOBMAOA | |
| SCHEMBL6703960 | 0.78 | MAOB (0.54) | MAOBFFAR1 | |
| SCHEMBL6692779 | 0.77 | BCHE (0.42) | MEN1KMT2ANPSR1FFAR4 | |
| SCHEMBL6698255 | 0.76 | PTPRZ1 (0.54) | PTPRZ1SCN9AMAOBMAOA | |
| SCHEMBL6698258 | 0.76 | PTPRZ1 (0.54) | PTPRZ1SCN9AMAOBMAOA | |
| SCHEMBL30745904 | 0.73 | PTPRZ1 (0.72) | PTPRZ1MAOB | |
| SCHEMBL30885390 | 0.72 | PTPRZ1 (0.67) | PTPRZ1MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |