Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690744 | 1.00 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6685320 | 0.94 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6690285 | 0.94 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6690105 | 0.94 | SMN1; SMN2 (0.56) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6690108 | 0.94 | SMN1; SMN2 (0.56) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6686469 | 0.87 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6686470 | 0.87 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6687911 | 0.86 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6687908 | 0.86 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6690014 | 0.84 | MTNR1A (0.54) | ALDH1A1BCHERAB9ACTSDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |