Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.62 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7233472 | 0.92 | RAB9A (0.64) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7301613 | 0.91 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL27888737 | 0.82 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL14275545 | 0.81 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL5475061 | 0.80 | SLC18A3 (0.71) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL5475054 | 0.80 | SLC18A3 (0.71) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL3455961 | 0.80 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL9001940 | 0.78 | GAA (0.70) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL15498626 | 0.77 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL11293119 | 0.77 | GAA (0.85) | ALDH1A1SMN1; SMN2MAPTHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |