Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.69 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690761 | 0.91 | ALDH1A1 (0.67) | ALDH1A1PABPC1EIF4HGAASMN1; SMN2 | |
| SCHEMBL3455961 | 0.85 | ALDH1A1 (1.00) | ALDH1A1PABPC1EIF4HGAASMN1; SMN2 | |
| SCHEMBL9001940 | 0.84 | GAA (0.70) | ALDH1A1PABPC1EIF4HGAASMN1; SMN2 | |
| SCHEMBL11293119 | 0.83 | GAA (0.85) | ALDH1A1GAASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL357539 | 0.83 | GAA (0.68) | ALDH1A1PABPC1EIF4HGAASMN1; SMN2 | |
| SCHEMBL31668470 | 0.83 | GAA (0.68) | ALDH1A1PABPC1EIF4HGAASMN1; SMN2 | |
| SCHEMBL15070498 | 0.83 | GAA (0.68) | ALDH1A1PABPC1EIF4HGAASMN1; SMN2 | |
| SCHEMBL7233472 | 0.82 | RAB9A (0.64) | ALDH1A1PABPC1EIF4HGAASMN1; SMN2 | |
| SCHEMBL15498626 | 0.82 | ALDH1A1 (0.65) | ALDH1A1PABPC1EIF4HGAASMN1; SMN2 | |
| SCHEMBL27303865 | 0.82 | MAPT (0.84) | ALDH1A1PABPC1EIF4HGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |