Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL3475846 | 0.96 | CA12 (0.50) | RXRARXRBKMT2AMEN1CA12 | |
| Isophthalic Acid SCHEMBL5558793 | 0.96 | CA12 (0.50) | RXRARXRBKMT2AMEN1CA12 | |
| Isophthalic Acid SCHEMBL3298198 | 0.96 | CA12 (0.50) | RXRARXRBKMT2AMEN1CA12 | |
| Isophthalic Acid SCHEMBL8373778 | 0.93 | RXRA (0.47) | RXRARXRBKMT2AMEN1CA12 | |
| Terephthalic Acid SCHEMBL28162786 | 0.91 | NPC1 (0.44) | RXRARXRBKMT2AMEN1CA12 | |
| Benzoic Acid SCHEMBL204568 | 0.88 | TSHR (0.61) | RXRARXRBKMT2AMEN1TSHR | |
| Benzoic Acid SCHEMBL226249 | 0.88 | TSHR (0.61) | RXRARXRBKMT2AMEN1TSHR | |
| Terephthalic Acid SCHEMBL6388159 | 0.88 | TSHR (0.57) | RXRARXRBKMT2AMEN1CA12 | |
| Isophthalic Acid SCHEMBL8944713 | 0.88 | RXRA (0.44) | RXRARXRBKMT2ACA12CA1 | |
| Isophthalic Acid SCHEMBL28396235 | 0.88 | RXRA (0.44) | RXRARXRBKMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340841-B | Polyurethane hot melt adhesive for bonding automobile exterior trim parts and preparation method thereof | 北京高盟新材料股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-111876107-B | Epoxy polyurethane modified acrylic resin adhesive and preparation method and application thereof | 杭州星华反光材料股份有限公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-111876107-A | Epoxy polyurethane modified acrylic resin adhesive and preparation method and application thereof | 杭州星华反光材料股份有限公司 | 2020-11-03 | — | — | CN | disclosed |
| WO-2004069896-A1 | PROCESS FOR PRODUCING NEOPENTYL-GLYCOL BASED POLYESTERS | SURFACE SPECIALTIES, S.A. (BE) | 2004-08-19 | — | — | WO | disclosed |
| EP-0201168-B1 | HIGH TEMPERATURE WIRE COATING POWDER, WIRE PROVIDED WITH A COATING AND METHOD OF PROVIDING A COATING ON A WIRE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0201168-A1 | High temperature wire coating powder, wire provided with a coating and method of providing a coating on a wire | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-11-12 | — | — | EP | disclosed |
| US-4605710-A | High temperature wire coating powder | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-08-12 | — | — | US | disclosed |