Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.49 |
| ▸ | CTSS | P25774 | 13/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694065 | 0.86 | CTSL (0.61) | CTSLCTSSCTSKATM | |
| SCHEMBL6687342 | 0.77 | NPC1 (0.51) | ATMGAASMN1; SMN2KMT2A | |
| SCHEMBL4800528 | 0.76 | CTSL (0.75) | CTSLCTSSCTSK | |
| SCHEMBL4800543 | 0.76 | CTSL (0.75) | CTSLCTSSCTSK | |
| SCHEMBL6686226 | 0.72 | CTSL (0.51) | CTSLCTSSCTSK | |
| SCHEMBL12443609 | 0.70 | NPC1 (0.62) | ATMGAASMN1; SMN2KMT2A | |
| SCHEMBL7044563 | 0.70 | TCF4 (0.53) | GAASMN1; SMN2KMT2A | |
| SCHEMBL6689745 | 0.70 | CTSL (0.75) | CTSLCTSSCTSK | |
| SCHEMBL4248125 | 0.69 | KCNK3 (0.82) | SMN1; SMN2KCNK3KMT2A | |
| SCHEMBL18773965 | 0.69 | NPC1 (0.64) | GAASMN1; SMN2KCNK3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |