Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 19/20 | 0.61 |
| ▸ | CTSS | P25774 | 17/20 | 0.61 |
| ▸ | CTSK | P43235 | 7/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690816 | 0.86 | CTSL (0.49) | CTSLCTSSCTSKATM | |
| SCHEMBL4802738 | 0.76 | CTSS (1.00) | CTSLCTSSCTSK | |
| SCHEMBL4796814 | 0.76 | CTSS (1.00) | CTSLCTSSCTSK | |
| SCHEMBL4797519 | 0.76 | CTSS (1.00) | CTSLCTSSCTSK | |
| SCHEMBL4796808 | 0.76 | CTSS (1.00) | CTSLCTSSCTSK | |
| SCHEMBL6687342 | 0.74 | NPC1 (0.51) | ATM | |
| SCHEMBL6686226 | 0.74 | CTSL (0.51) | CTSLCTSSCTSK | |
| SCHEMBL6689745 | 0.73 | CTSL (0.75) | CTSLCTSSCTSK | |
| SCHEMBL6687754 | 0.71 | CTSL (0.69) | CTSLCTSSCTSK | |
| SCHEMBL5843295 | 0.71 | CTSL (0.92) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |