Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687555 | 0.91 | MAPT (0.55) | RAB9AMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL6687401 | 0.91 | MAPT (0.55) | RAB9AMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL6686970 | 0.87 | MAPT (0.74) | RAB9AMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL5606372 | 0.78 | MAPT (0.65) | RAB9AMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL14366818 | 0.76 | MAPT (0.71) | RAB9AMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL6687343 | 0.75 | MAPT (1.00) | RAB9AMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL6689426 | 0.74 | MAPT (0.51) | RAB9AMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL14366837 | 0.71 | MAPT (0.82) | RAB9AMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL6692443 | 0.70 | ALDH1A1 (0.92) | RAB9AMAPTNPC1L3MBTL1ALDH1A1 | |
| SCHEMBL6691634 | 0.70 | MAPT (0.60) | RAB9AMAPTNPC1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |