Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366818 | 0.87 | MAPT (0.71) | MAPTALDH1A1LMNAHTTHIF1A | |
| SCHEMBL14366833 | 0.85 | ALDH1A1 (0.69) | MAPTALDH1A1LMNAHTTHIF1A | |
| SCHEMBL14366837 | 0.81 | MAPT (0.82) | MAPTALDH1A1LMNAHTTHIF1A | |
| SCHEMBL6692443 | 0.81 | ALDH1A1 (0.92) | MAPTALDH1A1LMNAHTTHIF1A | |
| SCHEMBL6691634 | 0.80 | MAPT (0.60) | MAPTALDH1A1LMNAHTTHIF1A | |
| SCHEMBL6686970 | 0.79 | MAPT (0.74) | MAPTALDH1A1LMNAHTTHIF1A | |
| SCHEMBL14366836 | 0.79 | ALDH1A1 (1.00) | MAPTALDH1A1LMNAHTTHIF1A | |
| SCHEMBL6690846 | 0.78 | RAB9A (0.60) | MAPTALDH1A1LMNAHTTHIF1A | |
| SCHEMBL6694656 | 0.77 | MAPT (0.71) | MAPTALDH1A1LMNAHTTHIF1A | |
| SCHEMBL6687343 | 0.76 | MAPT (1.00) | MAPTALDH1A1LMNAHTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070269420-A1 | Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases | VIROPHARMA INCORPORATED | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070269420-A1 | Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases | HAVCR2, FABP1, LIPC | MAPT 4287/4885ALDH1A1 971/4885LMNA 1671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.