SCHEMBL6690916

SCHEMBL6690916

COc1c2cc(C(C)(C)C)cc1Cc1cccc(c1O)Cc1cc(C(C)(C)C)cc(c1OC)Cc1cccc(c1O)Cc1cc(C(C)(C)C)cc(c1OC)Cc1cccc(c1O)C2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.45
CD69 Q07108 1/20 0.45
PTPRC P08575 4/20 0.42
PTPN2 P17706 4/20 0.42
PTPN1 P18031 4/20 0.42
PTPRB P23467 4/20 0.42
PTPN11 Q06124 4/20 0.42
TLR4 O00206 3/20 0.40
CD14 P08571 3/20 0.40
LY96 Q9Y6Y9 3/20 0.40
GSTA1 P08263 4/20 0.35
GSTP1 P09211 4/20 0.35
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1144971 0.82 GSTA1 (0.41) CD69PTPRCPTPN2PTPN1PTPRB
SCHEMBL759347 0.82 GSTA1 (0.41) CD69PTPRCPTPN2PTPN1PTPRB
SCHEMBL12549814 0.80 CD69 (0.46) ELANECD69PTPRCPTPN2PTPN1
SCHEMBL12856783 0.79 PTPRC (0.45) PTPRCPTPN2PTPN1PTPRBPTPN11
SCHEMBL29945572 0.76 GABRA1 (0.50) ELANECD69PTPRCPTPN2PTPN1
SCHEMBL2471228 0.76 GABRA1 (0.50) ELANECD69PTPRCPTPN2PTPN1
SCHEMBL30547266 0.76 GABRA1 (0.50) ELANECD69PTPRCPTPN2PTPN1
SCHEMBL29517201 0.76 GABRA1 (0.50) ELANECD69PTPRCPTPN2PTPN1
SCHEMBL13620669 0.76 GABRA1 (0.50) ELANECD69PTPRCPTPN2PTPN1
SCHEMBL9910710 0.76 GABRA1 (0.50) ELANECD69PTPRCPTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004085441-A1 NEW CALIX ARENE COMPOUNDS, THEIR PROCESS OF PREPARATION AND THEIR USE, PARTICULARLY AS ENZYMATIC MIMES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2004-10-07 WO disclosed
WO-2004085442-A2 NEW CALIX ARENE COMPOUNDS, THEIR PROCESS OF PREPARATION AND THEIR USE, PARTICULARLY AS ENZYMATIC MIMES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2004-10-07 WO disclosed