Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTA1 | P08263 | 5/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 5/20 | 0.41 |
| ▸ | PTPRC | P08575 | 4/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | PTPRB | P23467 | 4/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.41 |
| ▸ | CD69 | Q07108 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144971 | 1.00 | GSTA1 (0.41) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL15541243 | 0.89 | KDM4E (0.43) | CD69ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL12856781 | 0.87 | GSTA1 (0.41) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| Hydroxyamine SCHEMBL11037119 | 0.86 | CD69 (0.44) | CD69ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL1145207 | 0.85 | GSTA1 (0.40) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL6690916 | 0.82 | ELANE (0.45) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL8556505 | 0.82 | GSTA1 (0.41) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL12856783 | 0.81 | PTPRC (0.45) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL2471777 | 0.81 | ALDH1A1 (0.48) | GSTA1GSTP1PTPRCPTPN2PTPN1 | |
| SCHEMBL29366399 | 0.81 | ALDH1A1 (0.48) | GSTA1GSTP1PTPRCPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307116-B1 | METHOD FOR SELECTIVELY EXTRACTING MEMBRANE PROTEINS USING CALIXARENES | CENTRE NAT RECH SCIENT (FR) | 2012-03-21 | — | — | EP | disclosed |
| EP-2307116-A1 | METHOD FOR SELECTIVELY EXTRACTING MEMBRANE PROTEINS USING CALIXARENES | Centre National de la Recherche Scientifique - CNRS (FR) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009144419-A1 | METHOD FOR SELECTIVELY EXTRACTING MEMBRANE PROTEINS USING CALIXARENES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2009-12-03 | — | — | WO | disclosed |
| EP-0572599-B1 | ION-SENSITIVE DYES | KODAK LTD (GB) | 1998-06-17 | — | — | EP | disclosed |
| US-5641684-A | Ion-sensitive dyes | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-06-24 | — | — | US | disclosed |
| WO-1993012428-A1 | ION-SENSITIVE DYES | KODAK LIMITED (GB) | 1993-06-24 | — | — | WO | disclosed |