Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781174 | 0.84 | GABRA1 (0.41) | GABRA1GABRB2SRD5A1ALDH1A1CYP3A4 | |
| SCHEMBL8668256 | 0.83 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1MAPTKDM4E | |
| SCHEMBL6690960 | 0.80 | GABRA1 (0.44) | GABRA1GABRB2SRD5A1ALDH1A1CYP3A4 | |
| SCHEMBL2479613 | 0.79 | ALDH1A1 (0.52) | GABRA1GABRB2ALDH1A1CYP3A4ALOX5 | |
| SCHEMBL27668292 | 0.79 | GABRA1 (0.38) | GABRA1GABRB2SRD5A1ALDH1A1CYP3A4 | |
| SCHEMBL4192226 | 0.78 | HPGD (0.45) | GABRA1GABRB2SRD5A1ALDH1A1CYP3A4 | |
| SCHEMBL69556 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2SRD5A1ALDH1A1CYP3A4 | |
| SCHEMBL9800336 | 0.77 | SRD5A1 (0.39) | GABRA1GABRB2SRD5A1ALDH1A1CYP3A4 | |
| SCHEMBL11667005 | 0.77 | TTR (0.42) | ALDH1A1GAAKMT2AXDHHPGD | |
| SCHEMBL460585 | 0.77 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1CYP3A4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052814-A1 | PROCESS FOR THE PREPARATION OF A COSMETIC ACTIVE | UNILEVER PLC (GB) | 2004-06-24 | — | — | WO | disclosed |
| US-6172012-B1 | LUBRICATING GREASE COMPOSITION COMPRISING TITANIUM ALKOXIDE, CARBOXYLIC ACID, FATTY ACID, WATER, MINERAL OR SYNTHETIC OIL, EXTREME PRESSURE ADDITIVE COMPRISING ZINC DIALKYL DITHIOPHOSPHATE AND SULFURIZED FAT SOLID LUBRICANT | INDIAN OIL CORPORATION LIMITED (IN) | 2001-01-09 | — | — | US | disclosed |