SCHEMBL8668256

SCHEMBL8668256

C=CCc1cccc(OP(O)O)c1CC=C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 2/20 0.38
ADRB2 P07550 4/20 0.36
ADRB1 P08588 3/20 0.36
LMNA P02545 2/20 0.36
HTR1A P08908 1/20 0.36
ADRB3 P13945 1/20 0.36
ADRA2C P18825 1/20 0.36
SLC6A2 P23975 1/20 0.36
BDKRB2 P30411 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR2B P41595 1/20 0.36
KCNH2 Q12809 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1239929 0.86 GABRA1 (0.42) GABRA1GABRB2MAPTALDH1A1ADRB2
SCHEMBL1276594 0.85 PTGDR (0.34) GABRA1GABRB2MEN1MAPTMAPK1
SCHEMBL1160216 0.84 ALDH1A1 (0.47) GABRA1GABRB2ALDH1A1ADRB2ADRB1
SCHEMBL1268594 0.83 ALDH1A1 (0.41) GABRA1GABRB2MAPTALDH1A1ADRB2
SCHEMBL6690957 0.83 GABRA1 (0.36) GABRA1GABRB2MEN1MAPTMAPK1
SCHEMBL9777433 0.83 GABRA1 (0.38) GABRA1GABRB2MEN1MAPTMAPK1
SCHEMBL157454 0.82 GABRA1 (0.47) GABRA1GABRB2ALDH1A1ADRB2ADRB1
SCHEMBL10784215 0.81 GABRA1 (0.47) GABRA1GABRB2ALDH1A1ADRB2ADRB1
SCHEMBL2107709 0.77 GABRA1 (0.43) GABRA1GABRB2ALDH1A1ADRB2ADRB1
SCHEMBL18984961 0.77 ALDH1A1 (0.48) GABRA1GABRB2MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873315-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel Brønsted acid catalysts THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2024-01-16 US disclosed
CN-115803380-A Use of hydroxycinnamic acid salts for stabilizing organic materials, stabilized organic materials, method for stabilizing organic materials, specific stabilizers and stabilizer compositions 弗劳恩霍夫应用研究促进协会 2023-03-14 CN disclosed
CN-114746462-A Black-dyeing polyamide compositions, their preparation and use 巴斯夫欧洲公司 2022-07-12 CN disclosed
US-20220144868-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS The Board of Regents of the Nevada System of Higher Education on Behalf of the Univ of Nevada (US) 2022-05-12 US disclosed
US-11248014-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel bronsted acid catalysts THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2022-02-15 US disclosed
US-20210147457-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS 2021-05-20 US disclosed
WO-2018232315-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2018-12-20 WO disclosed
EP-0872507-A2 Process for the preparation of polycarbonates by melt-polycondensation DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-21 EP disclosed
EP-0861863-A2 Process for the preparation of polycarbonate by melt-polycondensation DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-09-02 EP disclosed
US-5670604-A USING AN ALKALI(METAL) BORATE CATALYST DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-09-23 US disclosed
US-5488094-A Process for the preparation of polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1996-01-30 US disclosed
US-5466775-A Melt polycondensation of a diphenol, compounds of an alkali metal and an alkali earth metal as catalysts DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-11-14 US disclosed
US-5405934-A Process for producing (co)polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-04-11 US disclosed
EP-0601602-A2 Process for producing (co)polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1994-06-15 EP disclosed
EP-0592900-A2 Process for the preparation of polycarbonates by melt-polycondensation DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-20 EP disclosed
EP-0336606-B1 COMPOSITION OF STABILIZED SYNTHETIC RESIN ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1993-09-08 EP disclosed
US-4885326-A 2,2'-ALKYLIDENE-BISPHENOL CYCLIC ALKYLPHOSPHITE AND 3,5-DIALKYL-4-HYDROXYPHENYLPROPIONIC ACID ESTER; HEAT, LIGHT, AND OXIDATION RESISTANCE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1989-12-05 US disclosed
EP-0336606-A1 Composition of stabilized synthetic resin ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1989-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147457-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS ELANE, PNKP, NHERF1 GABRA1 1543/4885GABRB2 2913/4885MEN1 3478/4885
US-11248014-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel bronsted acid catalysts ELANE, PNKP, NHERF1 GABRA1 1543/4885GABRB2 2913/4885MEN1 3478/4885
US-11873315-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel Brønsted acid catalysts ELANE, PNKP, SERPINB1 GABRA1 1124/4885GABRB2 2338/4885MEN1 4061/4885
US-20220144868-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS ELANE, PNKP, NHERF1 GABRA1 1543/4885GABRB2 2913/4885MEN1 3478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.