Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054954 | 0.75 | LMNA (0.54) | POLBALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL3778113 | 0.75 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C19MAPTKDM4E | |
| SCHEMBL6697640 | 0.74 | ALDH1A1 (0.49) | POLBALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL12083785 | 0.74 | PIK3CA (0.39) | ALDH1A1CYP1A2CYP2C19EGFRERBB2 | |
| SCHEMBL16919139 | 0.73 | ALDH1A1 (0.49) | POLBALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL6689839 | 0.72 | ATM (0.57) | POLBALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL6688131 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNA | |
| SCHEMBL26789531 | 0.72 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL18183958 | 0.71 | ANPEP (0.43) | POLBMAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL30797163 | 0.70 | NPSR1 (0.56) | MAPTKDM4EEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106292-A1 | HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| US-5530026-A | WITHOUT SYSTEMIC TOXICITY AND MUTAGENICITY | UNIVERSITE LAVAL (CA) | 1996-06-25 | — | — | US | disclosed |