Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698691 | 0.82 | HTR2A (0.33) | HTR2AHTR2CHTR1BHTR2BHTR1D | |
| SCHEMBL6691038 | 0.81 | TSHR (0.33) | HTR2AHTR2CHTR1BHTR2BHTR1D | |
| SCHEMBL6691232 | 0.78 | MEN1 (0.35) | MEN1NPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL6690278 | 0.75 | CYP1A2 (0.35) | KMT2ACYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL6694327 | 0.72 | RAB9A (0.34) | HTR2AHTR2CHTR1BHTR2BHTR1D | |
| SCHEMBL6691267 | 0.72 | NQO1 (0.34) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL6693788 | 0.70 | MEN1 (0.35) | MEN1NPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL6690892 | 0.64 | NQO1 (0.34) | MEN1NPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL6697925 | 0.62 | KMT2A (0.37) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL29919785 | 0.60 | CA12 (0.56) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |