SCHEMBL6691383

SCHEMBL6691383

C=C(C)c1ccc(OC(C)(CCC)OC)cc1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.38
MAPT P10636 1/20 0.33
NR1I2 O75469 1/20 0.33
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HIF1A Q16665 1/20 0.30
EPAS1 Q99814 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6699152 0.91 HDAC3 (0.35) ELANEMAPTNR1I2HDAC3HDAC1
SCHEMBL6693605 0.87 MAPT (0.35) ELANEMAPTNR1I2ALDH1A1
SCHEMBL6689382 0.86 ELANE (0.37) ELANEHDAC3HDAC1HDAC2
SCHEMBL6692034 0.86 ELANE (0.37) ELANEHDAC3HDAC1HDAC2HIF1A
SCHEMBL6692063 0.85 ELANE (0.36) ELANE
SCHEMBL6691454 0.84 ELANE (0.35) ELANEMAPTHDAC3HDAC1HDAC2
SCHEMBL6693598 0.84 ELANE (0.35) ELANEMAPT
SCHEMBL5367199 0.82 ELANE (0.41) ELANEMAPTNR1I2HDAC3HDAC1
SCHEMBL6693738 0.81 TP53 (0.38) ELANEMAPT
SCHEMBL6689635 0.80 TP53 (0.40) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0959389-B1 Diazodisulfone compound and radiation-sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6143460-A PHOTOACID GENERATOR PROVIDING IMPROVED PHOTORESIST RESOLUTION JSR CORPORATION (JP) 2000-11-07 US disclosed
EP-0959389-A1 Diazodisulfone compound and radiation-sensitive resin composition JSR Corporation (JP) 1999-11-24 EP disclosed