Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.45 |
| ▸ | TOP1 | P11387 | 3/20 | 0.45 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676197 | 0.77 | CHRM1 (0.54) | CHRM1FOXO1HPGDLMNAPOLB | |
| SCHEMBL25069761 | 0.74 | FOXO1 (0.66) | TOP1FOXO1HPGDLMNAPOLB | |
| SCHEMBL10673634 | 0.73 | CHRM1 (0.46) | CHRM1HPGDLMNAPOLBTAAR1 | |
| SCHEMBL6696933 | 0.73 | CHRM1 (0.47) | CHRM1FOXO1HPGDLMNAPOLB | |
| SCHEMBL6696925 | 0.73 | CHRM1 (0.47) | CHRM1FOXO1HPGDLMNAPOLB | |
| 7-Desethyl-Norfloxacin SCHEMBL30610053 | 0.73 | TOP1 (0.70) | TOP1HPGDLMNAPOLBTAAR1 | |
| 7-Desethyl-Norfloxacin SCHEMBL5551203 | 0.73 | TOP1 (0.70) | TOP1HPGDLMNAPOLBTAAR1 | |
| Trifluoroacetic Acid SCHEMBL4172072 | 0.72 | LMNA (0.57) | TOP1LMNAPOLBALDH1A1KDM4E | |
| 7-Desethyl-Norfloxacin SCHEMBL29548802 | 0.72 | TOP1 (0.68) | TOP1HPGDLMNAPOLBTAAR1 | |
| Trifluoroacetic Acid SCHEMBL3977476 | 0.71 | LMNA (0.53) | TOP1HPGDLMNAPOLBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101589-A1 | NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-11-25 | — | — | WO | disclosed |