Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696925 | 0.98 | CHRM1 (0.47) | CHRM1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6696929 | 0.88 | KDM4E (0.42) | CHRM1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6697736 | 0.86 | HTT (0.48) | CHRM1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6693095 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL10676197 | 0.80 | CHRM1 (0.54) | CHRM1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10676232 | 0.73 | KDM4E (0.54) | CHRM1KDM4EALDH1A1HPGDHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL6691389 | 0.73 | CHRM1 (0.45) | CHRM1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9590459 | 0.70 | STAT3 (0.60) | CHRM1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8627262 | 0.70 | ALDH1A1 (0.54) | CHRM1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8160866 | 0.70 | LMNA (0.53) | CHRM1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101589-A1 | NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-11-25 | — | — | WO | disclosed |