Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4920382 | 0.81 | MAPT (0.65) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL5713545 | 0.79 | MAPT (0.67) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL6694058 | 0.77 | MAPT (0.84) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL4919617 | 0.76 | MEN1 (0.65) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL2753869 | 0.75 | KMT2A (0.70) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL2754063 | 0.74 | MEN1 (0.60) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL3057573 | 0.73 | LMNA (0.60) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL21821838 | 0.73 | MAPT (0.76) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL4816530 | 0.72 | MEN1 (0.72) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL665000 | 0.72 | TP53 (0.81) | LMNAMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078115-A2 | BENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF ROTAVIRUS INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA, INCORPORATED (US) | 2004-09-16 | — | — | WO | claimed |