Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.68 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.68 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.68 |
| ▸ | GGT1 | P19440 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CFD | P00746 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695632 | 0.84 | CFD (0.61) | KDM4EHSD17B10HPGDALDH1A1PTGS1 | |
| SCHEMBL1997846 | 0.81 | HTT (0.58) | KDM4EHSD17B10HPGDALDH1A1PTGS1 | |
| Aspirin SCHEMBL1353 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10HPGDALDH1A1PTGS1 | |
| Aspirin SCHEMBL10456693 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10HPGDALDH1A1PTGS1 | |
| Aspirin SCHEMBL7580 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10HPGDALDH1A1PTGS1 | |
| Aspirin SCHEMBL29350479 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10HPGDALDH1A1PTGS1 | |
| Aspirin SCHEMBL1331740 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10HPGDALDH1A1PTGS1 | |
| SCHEMBL8676659 | 0.80 | KDM4E (0.70) | KDM4EHSD17B10HPGDALDH1A1PTGS1 | |
| SCHEMBL1156927 | 0.80 | KDM4E (0.70) | KDM4EHSD17B10HPGDALDH1A1PTGS1 | |
| SCHEMBL6178884 | 0.80 | KDM4E (0.70) | KDM4EHSD17B10HPGDALDH1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |