SCHEMBL6691666

SCHEMBL6691666

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CC=Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.39
PAM P19021 1/20 0.39
HTR2A P28223 3/20 0.37
S1PR4 O95977 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
S1PR1 P21453 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MAOB P27338 2/20 0.35
NFE2L2 Q16236 1/20 0.35
PTPRC P08575 1/20 0.34
PTPN1 P18031 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792774 0.98 IDO1 (0.40) IDO1PAMHTR2AS1PR4ALDH1A1
SCHEMBL7791511 0.93 IDO1 (0.41) IDO1PAMHTR2AS1PR4ALDH1A1
SCHEMBL7790769 0.79 LMNA (0.43) IDO1PAMHTR2AS1PR4ALDH1A1
SCHEMBL31414061 0.78 IDO1 (0.48) IDO1PAMHTR2AALDH1A1LMNA
SCHEMBL7792765 0.78 IDO1 (0.48) IDO1PAMHTR2AALDH1A1LMNA
SCHEMBL7783039 0.75 ALDH1A1 (0.44) IDO1PAMHTR2AS1PR4ALDH1A1
SCHEMBL8624263 0.74 IDO1 (0.44) IDO1PAMHTR2AS1PR4ALDH1A1
SCHEMBL5365860 0.73 LMNA (0.36) LMNA
SCHEMBL5374505 0.73 LMNA (0.36) LMNA
SCHEMBL10338474 0.73 IDO1 (0.44) IDO1PAMHTR2AS1PR4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6737225-B2 Method of undercutting micro-mechanical device with super-critical carbon dioxide TEXAS INSTRUMENTS INCORPORATED 2004-05-18 US disclosed
US-20030124462-A1 Method of undercutting micro-mechanical device with super-critical carbon dioxide TEXAS INSTRUMENTS INCORPORATED 2003-07-03 US disclosed