Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DTYMK | P23919 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969704 | 0.76 | CA12 (0.35) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL3729139 | 0.72 | TSHR (0.46) | CA12CA1CA9ALDH1A1MEN1 | |
| SCHEMBL4204234 | 0.72 | DTYMK (0.46) | CA12CA1CA9DTYMKALDH1A1 | |
| SCHEMBL1464495 | 0.72 | DTYMK (0.46) | CA12CA1CA9DTYMKALDH1A1 | |
| SCHEMBL6006263 | 0.71 | TSHR (0.56) | ALDH1A1MEN1MAPTKMT2APKM | |
| SCHEMBL5657466 | 0.69 | TSHR (0.38) | DTYMKALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL30252887 | 0.69 | TDP1 (0.54) | DTYMKALDH1A1MAPTPKMLMNA | |
| SCHEMBL15956316 | 0.69 | ALDH1A1 (0.53) | CA12CA9ALDH1A1MAPTKMT2A | |
| SCHEMBL4904 | 0.67 | POLB (0.57) | CA12CA1CA9DTYMKALDH1A1 | |
| SCHEMBL1043222 | 0.67 | POLB (0.57) | CA12CA1CA9DTYMKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072785-A1 | Intravascular delivery of non-viral nucleic acid | WOLFF JON A (US) | 2004-04-15 | — | — | US | disclosed |
| EP-1102784-A1 | A COMPOUND CONTAINING A LABILE DISULFIDE BOND | Mirus Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000075162-A1 | A COMPOUND CONTAINING A LABILE DISULFIDE BOND | MIRUS CORPORATION (US) | 2000-12-14 | — | — | WO | disclosed |