Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690806 | 0.83 | RAB9A (0.67) | MAPTMEN1KMT2AL3MBTL1PLA2G1B | |
| SCHEMBL6698052 | 0.82 | MAPT (0.53) | MAPTMEN1KMT2AL3MBTL1PLA2G1B | |
| SCHEMBL6691471 | 0.82 | UTS2R (0.56) | MAPTMEN1KMT2AL3MBTL1PLA2G1B | |
| SCHEMBL11512000 | 0.81 | MAPT (0.62) | MAPTMEN1KMT2AL3MBTL1PLA2G1B | |
| SCHEMBL11511314 | 0.78 | MEN1 (0.68) | MAPTMEN1KMT2AL3MBTL1PLA2G1B | |
| SCHEMBL6495858 | 0.78 | MAPT (0.50) | MAPTMEN1KMT2AL3MBTL1PLA2G1B | |
| SCHEMBL14489529 | 0.78 | SLC22A12 (0.51) | MAPTMEN1KMT2AL3MBTL1PLA2G1B | |
| SCHEMBL7988500 | 0.77 | RAB9A (0.65) | MAPTMEN1KMT2AL3MBTL1PLA2G1B | |
| SCHEMBL632689 | 0.77 | KCNJ5 (0.60) | MAPTMEN1KMT2AL3MBTL1PLA2G1B | |
| SCHEMBL6492819 | 0.77 | RAB9A (0.49) | MAPTMEN1KMT2AL3MBTL1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | 4SC AG (DE) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | PAH, PNMT, OPRM1 | MAPT 3951/4885MEN1 960/4885KMT2A 998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.