Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390783 | 0.91 | BRD4 (0.53) | BRD4CYP2D6SRCHPGDLMNA | |
| SCHEMBL1742565 | 0.82 | SRC (0.59) | CYP2D6SRCLMNAMAPK1KMT2A | |
| SCHEMBL10869302 | 0.81 | MMP8 (0.51) | BRD4MAPK1KMT2AMAPTGAA | |
| SCHEMBL107151 | 0.79 | HPGD (0.48) | BRD4CYP2D6SRCHPGDLMNA | |
| SCHEMBL6689864 | 0.79 | CYP2D6 (0.44) | CYP2D6SRCHPGDLMNAMAPK1 | |
| SCHEMBL10079016 | 0.77 | DPP4 (0.48) | CYP2D6SRCHPGDLMNAMAPK1 | |
| SCHEMBL15686539 | 0.77 | DPP4 (0.48) | CYP2D6SRCHPGDLMNAMAPK1 | |
| SCHEMBL11158839 | 0.77 | LMNA (0.44) | BRD4CYP2D6SRCHPGDLMNA | |
| SCHEMBL9844153 | 0.76 | EPHX1 (0.48) | CYP2D6SRCLMNAMAPK1CES2 | |
| SCHEMBL6159580 | 0.76 | CYP2D6 (0.46) | CYP2D6SRCHPGDLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |