Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742565 | 0.82 | SRC (0.59) | CYP2D6SRCLMNAMAPK1CYP1A2 | |
| SCHEMBL9844391 | 0.80 | CTRB1 (0.42) | LMNACYP1A2ALOX5CTSDCYP2C19 | |
| SCHEMBL5834050 | 0.79 | LMNA (0.48) | EPHX1CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL15577857 | 0.79 | DPP4 (0.50) | EPHX1CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL3611836 | 0.79 | DPP4 (0.50) | EPHX1CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL11022438 | 0.79 | CYP2D6 (0.56) | EPHX1CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL341787 | 0.77 | ALOX5 (0.50) | EPHX1CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL23052844 | 0.77 | ALOX5 (0.55) | EPHX1CYP2D6SRCLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL3618508 | 0.77 | DPP4 (0.48) | EPHX1CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL1537326 | 0.77 | EPHX1 (0.46) | EPHX1CYP2D6SRCLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |
| CN-1051733-A | Acyl-CoA: cholesteryl transferase inhibitor | WARNER LAMBERT CO (US) | 1991-05-29 | — | — | CN | disclosed |