Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 3/20 | 0.44 |
| ▸ | ILK | Q13418 | 2/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1884283 | 0.78 | AGPAT2 (0.44) | AGPAT2ILKAKR1B1AKR1B10AKR1A1 | |
| SCHEMBL2138665 | 0.70 | ILK (0.54) | AGPAT2ILKDYRK1AKDM4EALDH1A1 | |
| SCHEMBL6691854 | 0.70 | AGPAT2 (0.46) | AGPAT2ILKMAT2AAKR1B1AKR1B10 | |
| SCHEMBL12470403 | 0.66 | ILK (0.56) | AGPAT2ILKDYRK1AKDM4EALDH1A1 | |
| SCHEMBL29348201 | 0.66 | CYP2A6 (0.48) | POLB | |
| SCHEMBL7259223 | 0.66 | AGPAT2 (0.60) | AGPAT2ILKDYRK1AKDM4EALDH1A1 | |
| SCHEMBL12470914 | 0.66 | ILK (0.52) | AGPAT2ILKDYRK1AKDM4EALDH1A1 | |
| SCHEMBL11011940 | 0.65 | ILK (0.52) | AGPAT2ILKAKR1B1AKR1B10AKR1A1 | |
| SCHEMBL1885251 | 0.65 | GRIA1 (0.51) | AGPAT2ILKAKR1B1AKR1B10AKR1A1 | |
| SCHEMBL8704110 | 0.65 | KDM4E (0.55) | AGPAT2ILKDYRK1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465626-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY OR AN ANTIINFLAMMATORY AGENT AND THEIR USES | Eisai Co., Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003047577-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY OR AN ANTIINFLAMMATORY AGENT AND THEIR USES | EISAI CO LTD (JP) | 2003-06-12 | — | — | WO | disclosed |