SCHEMBL6692079

SCHEMBL6692079

CC(=O)Oc1ccc(C(=O)O)c(Cl)c1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 2/20 0.56
KDM4E B2RXH2 8/20 0.55
ALDH1A1 P00352 5/20 0.55
TSHR P16473 5/20 0.55
HSD17B10 Q99714 4/20 0.55
TDP1 Q9NUW8 4/20 0.55
HPGD P15428 3/20 0.55
PTGS1 P23219 2/20 0.55
PTGS2 P35354 2/20 0.55
ESR1 P03372 1/20 0.55
ITGB3 P05106 1/20 0.55
ITGA2B P08514 1/20 0.55
HMGB1 P09429 1/20 0.55
GGT1 P19440 1/20 0.55
BLM P54132 1/20 0.55
NAPRT Q6XQN6 1/20 0.55
MAPK1 P28482 2/20 0.50
USP2 O75604 1/20 0.49
CYP2C19 P33261 1/20 0.49
LMNA P02545 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9356004 0.86 MAPK1 (0.60) CFDKDM4EALDH1A1TSHRHSD17B10
SCHEMBL6693412 0.84 KDM4E (0.68) CFDKDM4EALDH1A1TSHRHSD17B10
SCHEMBL11541423 0.83 MAPT (0.59) CFDKDM4EALDH1A1TSHRHSD17B10
SCHEMBL30949565 0.81 TDP1 (0.55) KDM4EALDH1A1TSHRHSD17B10TDP1
SCHEMBL6931814 0.81 TDP1 (0.55) KDM4EALDH1A1TSHRHSD17B10TDP1
SCHEMBL17799604 0.80 CFD (0.47) CFDKDM4EALDH1A1TSHRHSD17B10
SCHEMBL11540900 0.80 MAPT (0.52) KDM4EALDH1A1TSHRHSD17B10TDP1
SCHEMBL11057308 0.79 KDM4E (0.46) CFDKDM4EALDH1A1TSHRHSD17B10
SCHEMBL8860109 0.79 KDM4E (0.50) CFDKDM4EALDH1A1TSHRHSD17B10
SCHEMBL31612516 0.79 KDM4E (0.50) CFDKDM4EALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0950669-B1 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM & HAAS (US) 2004-09-08 EP disclosed
US-6306991-B1 TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS ROHM AND HAAS COMPANY 2001-10-23 US disclosed
US-6149977-A CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. ROHM AND HAAS COMPANY (US) 2000-11-21 US disclosed
EP-0950669-A2 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM AND HAAS COMPANY (US) 1999-10-20 EP disclosed
US-4574066-A MELT POLYMERIZATION CATALYZED BY POTASSIUM ACETATE CELANESE CORPORATION (US) 1986-03-04 US disclosed