Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693305 | 0.85 | TDP1 (0.50) | TDP1L3MBTL1CYP4F2CYP4A11F10 | |
| SCHEMBL6692005 | 0.85 | TDP1 (0.50) | TDP1L3MBTL1CYP4F2CYP4A11F10 | |
| SCHEMBL6695028 | 0.85 | TDP1 (0.50) | TDP1L3MBTL1CYP4F2CYP4A11F10 | |
| SCHEMBL9201038 | 0.83 | LMNA (0.57) | TDP1CYP4F2CYP4A11F10SERPINE1 | |
| Butane SCHEMBL1041490 | 0.82 | MAPT (0.50) | TDP1L3MBTL1CYP4F2CYP4A11F10 | |
| SCHEMBL6693904 | 0.81 | ESR1 (0.56) | TDP1L3MBTL1F10MAPTMEN1 | |
| SCHEMBL10727789 | 0.81 | KMT2A (0.52) | TDP1CYP4F2CYP4A11F10MEN1 | |
| SCHEMBL931171 | 0.80 | MEN1 (0.52) | TDP1L3MBTL1CYP4F2CYP4A11F10 | |
| SCHEMBL6688930 | 0.80 | AKR1C3 (0.56) | KMT2APOLBNPC1RAB9A | |
| SCHEMBL1248647 | 0.80 | SMN1; SMN2 (0.65) | CYP4F2CYP4A11MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |