Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27935114 | 0.88 | LMNA (0.58) | LMNACYP3A4MAPTTDP1SERPINE1 | |
| SCHEMBL8475427 | 0.86 | LMNA (0.51) | LMNACYP3A4MAPTTDP1SERPINE1 | |
| Ethyl Benzoate SCHEMBL14931241 | 0.85 | ELANE (0.59) | LMNACYP3A4MAPTTDP1MEN1 | |
| SCHEMBL3015445 | 0.85 | ELANE (0.49) | CYP4F2CYP4A11MAPTTDP1SERPINE1 | |
| SCHEMBL27452214 | 0.84 | LMNA (0.54) | LMNACYP3A4MAPTTDP1MEN1 | |
| SCHEMBL931171 | 0.84 | MEN1 (0.52) | CYP4F2CYP4A11MAPTTDP1MEN1 | |
| SCHEMBL1248647 | 0.83 | SMN1; SMN2 (0.65) | LMNACYP4F2CYP4A11MAPTMEN1 | |
| SCHEMBL1989713 | 0.83 | KMT2A (0.62) | LMNACYP4F2CYP4A11MAPTTDP1 | |
| SCHEMBL6692126 | 0.83 | TDP1 (0.50) | CYP4F2CYP4A11MAPTTDP1SERPINE1 | |
| SCHEMBL6692005 | 0.83 | TDP1 (0.50) | CYP4F2CYP4A11MAPTTDP1SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |