Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298308 | 0.80 | ALDH1A1 (0.33) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL29367967 | 0.80 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL3051883 | 0.80 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL3051884 | 0.80 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL11297577 | 0.73 | ALOX15 (0.33) | — | |
| SCHEMBL9461967 | 0.73 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL9817169 | 0.73 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL9461969 | 0.73 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL16683369 | 0.71 | NPSR1 (0.45) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL27889220 | 0.71 | KEAP1 (0.30) | HCAR2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396354-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023075766-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023049475-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| EP-4153604-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2023-03-29 | — | — | EP | disclosed |
| EP-4125893-A1 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | Biohaven Therapeutics Ltd. (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-4061425-A1 | DIRECTED CONJUGATION TECHNOLOGIES | Kleo Pharmaceuticals, Inc. (US) | 2022-09-28 | — | — | EP | disclosed |
| EP-4022059-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2022-07-06 | — | — | EP | disclosed |
| EP-3993818-A2 | CD38-BINDING AGENTS AND USES THEREOF | Kleo Pharmaceuticals, Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| WO-2021257884-A1 | VACCINES, VACCINE PRIMING, AND ANTIGEN DOSE SPARING | ADJUVANCE TECHNOLOGIES, INC. (US) | 2021-12-23 | — | — | WO | disclosed |
| WO-2021237223-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| WO-2021195401-A1 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-09-30 | — | — | WO | disclosed |
| WO-2021102052-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |
| WO-2021071858-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021003050-A2 | CD38-BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |
| EP-3630199-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018223056-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2018-12-06 | — | — | WO | disclosed |
| EP-2606056-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024604-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | WO | disclosed |