Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734543 | 0.88 | HNF4A (0.51) | FOLH1FABP3FABP4TSHRL3MBTL1 | |
| SCHEMBL23521242 | 0.87 | FOLH1 (0.53) | FOLH1FABP3FABP4TSHRKMT2A | |
| SCHEMBL4621115 | 0.86 | LDHA (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2LDHA | |
| SCHEMBL5720759 | 0.86 | ESR2 (0.44) | ESR2FOLH1FABP3FABP4TSHR | |
| SCHEMBL30371937 | 0.86 | LDHA (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2LDHA | |
| SCHEMBL1775363 | 0.86 | ESR2 (0.44) | ESR2FOLH1TSHRPDE10AKMT2A | |
| SCHEMBL6636942 | 0.85 | ESR2 (0.43) | ESR2FOLH1FABP3FABP4TSHR | |
| SCHEMBL29485413 | 0.84 | FOLH1 (0.53) | FOLH1FABP3FABP4TDP1L3MBTL1 | |
| SCHEMBL3229734 | 0.84 | FOLH1 (0.53) | FOLH1FABP3FABP4TDP1L3MBTL1 | |
| SCHEMBL9954274 | 0.83 | MEN1 (0.43) | ESR2FOLH1TSHRPDE10AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678809-B | Synthesis method and application of tetrazole functionalized UIO-67 | 山西大学 | 2020-09-29 | — | — | CN | claimed |
| CN-109678809-B | Synthesis method and application of tetrazole functionalized UIO-67 | 山西大学 | 2020-09-29 | — | — | CN | disclosed |
| WO-2004078180-A2 | NAALADASE INHIBITORS FOR TREATING OPIOID TOLERANCE | GUILFORD PHARMACEUTICALS INC. (US) | 2004-09-16 | — | — | WO | disclosed |
| EP-1292601-A2 | NAALADASE INHIBITORS FOR TREATING RETINAL DISORDERS AND GLAUCOMA | GUILFORD PHARMACEUTICALS INC. (US) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001092274-A2 | NAALADASE INHIBITORS FOR TREATING RETINAL DISORDERS AND GLAUCOMA | GUILFORD PHARMACEUTICALS INC. (US) | 2001-12-06 | — | — | WO | disclosed |