SCHEMBL3229734

SCHEMBL3229734

Cc1cccc(-c2ccccc2)c1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.53
MYC P01106 1/20 0.52
FABP4 P15090 2/20 0.49
FABP3 P05413 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HNF4A P41235 1/20 0.48
MCL1 Q07820 2/20 0.45
KMT2A Q03164 3/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
NR1H4 Q96RI1 2/20 0.43
HPGD P15428 2/20 0.43
MEN1 O00255 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
RPA1 P27694 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29485413 1.00 FOLH1 (0.53) FOLH1MYCFABP4FABP3TDP1
SCHEMBL3795573 0.89 L3MBTL1 (0.57) MYCFABP4FABP3TDP1L3MBTL1
SCHEMBL22703438 0.89 TDP1 (0.46) FOLH1MYCFABP4FABP3TDP1
SCHEMBL6679648 0.88 MYC (0.55) MYCFABP4FABP3TDP1L3MBTL1
SCHEMBL5725387 0.86 SMN1; SMN2 (0.46) FOLH1MYCFABP4FABP3L3MBTL1
SCHEMBL592209 0.85 LDHA (0.52) FOLH1MYCTDP1L3MBTL1MCL1
SCHEMBL8357034 0.85 TDP1 (0.44) FOLH1MYCFABP4FABP3TDP1
SCHEMBL593127 0.85 FOLH1 (0.61) FOLH1FABP4FABP3HNF4AKMT2A
SCHEMBL8572487 0.85 BCAT2 (0.53) FOLH1MYCFABP4FABP3HNF4A
SCHEMBL16698148 0.85 MYC (0.44) FOLH1MYCFABP4FABP3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
US-11091419-B2 Preparation and purification of biphenyldicarboxylic acids EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-08-17 US claimed
US-20210198173-A1 OXIDATION OF METHYL-SUBSTITUTED BIPHENYL COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC. 2021-07-01 US claimed
US-20200361847-A1 Preparation and Purification of Biphenyldicarboxylic Acids EXXONMOBIL CHEMICAL PATENTS INC. 2020-11-19 US claimed
US-20200325096-A1 Oxidation of Methyl-substituted Biphenyl Compounds EXXONMOBIL CHEMICAL PATENTS INC. 2020-10-15 US claimed
US-10351506-B2 Purified plasticizers, production and use EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-07-16 US claimed
WO-2019103756-A1 PREPARATION AND PURIFICATION OF BIPHENYLDICARBOXYLIC ACIDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-05-31 WO claimed
US-20190161429-A1 Aromatic Esters and Polyesters, Production Without Esterification Catalyst, and Use EXXONMOBIL CHEMICAL PATENTS INC. 2019-05-30 US claimed
EP-3475255-A1 AROMATIC ESTERS AND POLYESTERS, PRODUCTION WITHOUT ESTERIFICATION CATALYST, AND USE ExxonMobil Chemical Patents Inc. (US) 2019-05-01 EP claimed
EP-3440038-A2 OXIDATION OF METHYL-SUBSTITUTED BIPHENYL COMPOUNDS ExxonMobil Chemical Patents Inc. (US) 2019-02-13 EP claimed
US-20190031593-A1 Purified Plasticizers, Production and Use EXXONMOBIL CHEMICAL PATENTS INC. 2019-01-31 US claimed
CN-109195940-A Aromatic ester and polyester, the preparation and use without using esterification catalyst 埃克森美孚化学专利公司 2019-01-11 CN claimed
CN-108884002-A The oxidation of methyl substituted biphenol compound 埃克森美孚化学专利公司 2018-11-23 CN claimed
WO-2017222692-A1 AROMATIC ESTERS AND POLYESTERS, PRODUCTION WITHOUT ESTERIFICATION CATALYST, AND USE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-12-28 WO claimed
WO-2017204913-A2 PURIFIED PLASTICIZERS, PRODUCTION AND USE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-11-30 WO claimed
WO-2017176391-A2 OXIDATION OF METHYL-SUBSTITUTED BIPHENYL COMPOUNDS EXXONMOBILE CHEMICAL PATENTS INC. (US) 2017-10-12 WO claimed
US-20170253723-A1 Plasticizers Production and Use EXXONMOBIL CHEMICAL PATENTS INC. 2017-09-07 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
US-6491795-B2 DISTILLING RESIDUE REMAINING AFTER REMOVAL OF UNREACTED TOLUENE AND BENZOIC ACID FROM REACTION MIXTURE PRODUCED BY OXIDATION OF TOLUENE BY MOLECULAR OXYGEN IN THE PRESENCE OF A METAL CATALYST NIPPON STEEL CHEMICAL CO., LTD. (JP) 2002-12-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361847-A1 Preparation and Purification of Biphenyldicarboxylic Acids HPD, HMBS, MCCC2 FOLH1 330/4885MYC 3221/4885FABP4 343/4885
US-20200325096-A1 Oxidation of Methyl-substituted Biphenyl Compounds CYP1B1, CYP1A1, CYP4B1 FOLH1 2075/4885MYC 777/4885FABP4 404/4885
US-10351506-B2 Purified plasticizers, production and use ALKBH3, FTO, ALK FOLH1 4220/4885MYC 1007/4885FABP4 21/4885
US-20190031593-A1 Purified Plasticizers, Production and Use ALKBH3, FTO, ALK FOLH1 4220/4885MYC 1007/4885FABP4 21/4885
US-20170253723-A1 Plasticizers Production and Use PCBP1, CYP1B1, PBRM1 FOLH1 3603/4885MYC 657/4885FABP4 7/4885
US-20190161429-A1 Aromatic Esters and Polyesters, Production Without Esterification Catalyst, and Use PAH, ALKBH3, ALK FOLH1 2650/4885MYC 891/4885FABP4 213/4885
US-20210198173-A1 OXIDATION OF METHYL-SUBSTITUTED BIPHENYL COMPOUNDS CYP1B1, CYP1A1, CYP4B1 FOLH1 2075/4885MYC 777/4885FABP4 404/4885
US-11091419-B2 Preparation and purification of biphenyldicarboxylic acids HPD, HMBS, MCCC2 FOLH1 330/4885MYC 3221/4885FABP4 343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.