Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 2/20 | 0.41 |
| ▸ | CEPT1 | Q9Y6K0 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694405 | 0.84 | SMN1; SMN2 (0.45) | AGPAT2MAPTSMN1; SMN2POLBTHRB | |
| SCHEMBL6086300 | 0.78 | CEPT1 (0.47) | AGPAT2CEPT1MAPTRXFP1POLB | |
| SCHEMBL6688046 | 0.78 | CEPT1 (0.40) | AGPAT2CEPT1TOP2ACYP3A4POLB | |
| SCHEMBL6086055 | 0.73 | CEPT1 (0.39) | AGPAT2CEPT1TOP2AMAPTRXFP1 | |
| SCHEMBL6086493 | 0.71 | CEPT1 (0.48) | AGPAT2CEPT1MAPTRXFP1SMN1; SMN2 | |
| SCHEMBL6084017 | 0.71 | CEPT1 (0.52) | AGPAT2CEPT1TOP2AMAPTRXFP1 | |
| SCHEMBL6084212 | 0.71 | CEPT1 (0.51) | AGPAT2CEPT1MAPTRXFP1CYP1A2 | |
| SCHEMBL6085859 | 0.70 | CEPT1 (0.51) | AGPAT2CEPT1TOP2AMAPTRXFP1 | |
| SCHEMBL6087191 | 0.70 | CEPT1 (0.51) | AGPAT2CEPT1TOP2AMAPTRXFP1 | |
| SCHEMBL6688484 | 0.70 | CEPT1 (0.44) | AGPAT2CEPT1MAPTRXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002062804-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2002-08-15 | — | — | WO | disclosed |