Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693244 | 0.85 | MAPT (0.50) | MAPTCA2CYP2A6PKMKEAP1 | |
| SCHEMBL6692359 | 0.84 | MAPT (0.52) | MAPTCA2CYP2A6PKMKEAP1 | |
| SCHEMBL6695173 | 0.81 | MAPT (0.51) | MAPTCA2CYP2A6PKMKEAP1 | |
| SCHEMBL6697152 | 0.77 | MAPT (0.47) | MAPTCA2CYP2A6PKMKEAP1 | |
| SCHEMBL6692128 | 0.77 | MAPT (0.53) | MAPTCA2CYP2A6MEN1KMT2A | |
| SCHEMBL6690783 | 0.74 | RXFP1 (0.44) | MAPTCYP1A2CYP2C9CYP2C19PLA2G1B | |
| SCHEMBL6691456 | 0.72 | MEN1 (0.49) | MAPTCYP1A2CYP2C9CYP2C19PLA2G1B | |
| SCHEMBL6694360 | 0.72 | P2RX1 (0.47) | MAPTCA2CYP2A6PKMKEAP1 | |
| SCHEMBL6770216 | 0.71 | AHR (0.43) | MAPTCYP1A2CYP2C9CYP2C19PLA2G1B | |
| SCHEMBL657127 | 0.71 | CA2 (0.47) | MAPTCA2CYP2A6PKMKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | 4SC AG (DE) | 2004-01-15 | — | — | US | disclosed |
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | PAH, PNMT, OPRM1 | MAPT 3951/4885CA2 1332/4885CYP2A6 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.