Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688413 | 1.00 | CNR2 (0.51) | CNR2CNR1PARP1CA12CA1 | |
| SCHEMBL6703688 | 0.95 | PARP1 (0.49) | CNR2CNR1PARP1SIGMAR1POLB | |
| SCHEMBL6927393 | 0.91 | PARP1 (0.56) | CNR2PARP1POLBSMN1; SMN2SLC29A1 | |
| SCHEMBL6692750 | 0.89 | CNR2 (0.48) | CNR2CNR1PARP1CA12CA1 | |
| SCHEMBL6688415 | 0.89 | CNR2 (0.48) | CNR2CNR1PARP1CA12CA1 | |
| SCHEMBL6688045 | 0.86 | PARP1 (0.54) | PARP1SMN1; SMN2MEN1LMNATSHR | |
| SCHEMBL6930889 | 0.84 | CA12 (0.50) | CNR2PARP1CA12CA1CA2 | |
| SCHEMBL6692009 | 0.81 | CA12 (0.46) | CNR2CNR1PARP1CA12CA1 | |
| SCHEMBL7937028 | 0.81 | HPGD (0.53) | CNR2CNR1POLBSMN1; SMN2MEN1 | |
| SCHEMBL3226370 | 0.80 | LMNA (0.57) | PARP1SMN1; SMN2MEN1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |