Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226370 | 0.95 | LMNA (0.57) | PARP1SMN1; SMN2LMNAKMT2ATSHR | |
| SCHEMBL6927393 | 0.90 | PARP1 (0.56) | PARP1SMN1; SMN2LMNAKMT2ATSHR | |
| SCHEMBL6703688 | 0.88 | PARP1 (0.49) | PARP1SMN1; SMN2LMNAKMT2ATSHR | |
| SCHEMBL6688048 | 0.87 | PARP1 (0.54) | PARP1SMN1; SMN2LMNAKMT2ATSHR | |
| SCHEMBL6695768 | 0.86 | CYP2D6 (0.54) | PARP1SMN1; SMN2LMNAKMT2ATSHR | |
| SCHEMBL6688413 | 0.86 | CNR2 (0.51) | PARP1SMN1; SMN2LMNAKMT2ATSHR | |
| SCHEMBL6692746 | 0.86 | CNR2 (0.51) | PARP1SMN1; SMN2LMNAKMT2ATSHR | |
| SCHEMBL367502 | 0.83 | HPGD (0.65) | SMN1; SMN2LMNAKMT2ATSHRMAPK1 | |
| SCHEMBL14786240 | 0.83 | ALDH1A1 (0.62) | PARP1SMN1; SMN2LMNAKMT2ATSHR | |
| Benzamide SCHEMBL10722500 | 0.82 | BLM (0.60) | SMN1; SMN2LMNAKMT2AMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |