Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 7/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697097 | 0.92 | PARP1 (0.42) | CNR2PARP1 | |
| SCHEMBL6692012 | 0.87 | CA2 (0.42) | CA12CA1CA2CA9PLA2G2A | |
| SCHEMBL6692575 | 0.84 | LMNA (0.45) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL6692232 | 0.82 | KMT2A (0.49) | — | |
| SCHEMBL6688413 | 0.81 | CNR2 (0.51) | CA12CA1CA2CA9PLA2G2A | |
| SCHEMBL6692746 | 0.81 | CNR2 (0.51) | CA12CA1CA2CA9PLA2G2A | |
| SCHEMBL6703688 | 0.79 | PARP1 (0.49) | CNR2CNR1HRH2HRH1PARP1 | |
| SCHEMBL6697103 | 0.79 | PARP1 (0.43) | PARP1 | |
| SCHEMBL6687434 | 0.78 | HPGD (0.44) | CA12CA1CA2CA9PLA2G2A | |
| SCHEMBL6692407 | 0.76 | KMT2A (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |