SCHEMBL669296

SCHEMBL669296

COc1c(O)ccc(C=CC(=O)OC(C)c2ccccc2)c1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.53
TDP1 Q9NUW8 3/20 0.39
ABCB1 P08183 1/20 0.38
MAPT P10636 4/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 3/20 0.37
HPGD P15428 2/20 0.37
TP53 P04637 2/20 0.37
ALOX15 P16050 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
CAPN1 P07384 1/20 0.37
CTSL P07711 1/20 0.37
CTSB P07858 1/20 0.37
HTR1A P08908 1/20 0.36
AKR1B10 O60218 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28664191 0.84 MAPT (0.40) TDP1MAPTALDH1A1KDM4EHPGD
Benzene SCHEMBL28275342 0.80 CA1 (0.49) ABCB1MAPTALDH1A1KDM4EHPGD
SCHEMBL28518886 0.80 MAPT (0.56) TDP1MAPTALDH1A1KDM4EHPGD
SCHEMBL8011005 0.79 NFE2L2 (0.60) HCAR2MAPTKDM4EMEN1CYP1A2
SCHEMBL10875625 0.79 KDM4E (0.49) TDP1MAPTALDH1A1KDM4EHPGD
SCHEMBL2535572 0.79 KDM4E (0.49) TDP1MAPTALDH1A1KDM4EHPGD
SCHEMBL9641895 0.78 HCAR2 (0.63) HCAR2ALDH1A1KDM4EHPGDMEN1
SCHEMBL9641909 0.78 HCAR2 (0.63) HCAR2ALDH1A1KDM4EHPGDMEN1
SCHEMBL5610351 0.76 AKR1B10 (0.64) HCAR2TDP1MAPTALDH1A1KDM4E
SCHEMBL8011012 0.76 MAPT (0.62) HCAR2TDP1MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2605756-A2 FUNCTIONAL FOOD COMPOSITIONS AND METHODS Clearfarma Industries Ltd. (IL) 2013-06-26 EP disclosed
WO-2012023142-A2 FUNCTIONAL FOOD COMPOSITIONS AND METHODS CLEARFARMA INDUSTRIES LTD. (IL) 2012-02-23 WO disclosed