Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.46 |
| ▸ | HTR2A | P28223 | 14/20 | 0.46 |
| ▸ | HTR2B | P41595 | 14/20 | 0.46 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668663 | 0.93 | HTR2C (0.47) | HTR2CHTR2AHTR2BEIF2AK3CYP1A2 | |
| SCHEMBL6666452 | 0.91 | HTR2A (0.44) | HTR2CHTR2AHTR2BEIF2AK3CYP1A2 | |
| SCHEMBL6665112 | 0.86 | HTR2C (0.46) | HTR2CHTR2AHTR2BEIF2AK3CYP1A2 | |
| SCHEMBL6665020 | 0.86 | HTR2A (0.44) | HTR2CHTR2AHTR2BEIF2AK3CYP1A2 | |
| SCHEMBL6804211 | 0.84 | HTR2A (0.48) | HTR2CHTR2AHTR2BEIF2AK3SMO | |
| SCHEMBL6666719 | 0.83 | HTR2C (0.47) | HTR2CHTR2AHTR2BEIF2AK3CYP1A2 | |
| SCHEMBL6664848 | 0.83 | HTR2A (0.53) | HTR2CHTR2AHTR2BEIF2AK3SMO | |
| SCHEMBL6664767 | 0.83 | EIF2AK3 (0.46) | HTR2CHTR2AHTR2BEIF2AK3SMO | |
| SCHEMBL6662151 | 0.82 | HTR2A (0.48) | HTR2CHTR2AHTR2BEIF2AK3CYP1A2 | |
| SCHEMBL6664409 | 0.81 | EIF2AK3 (0.48) | HTR2CHTR2AHTR2BEIF2AK3SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |