Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CEL | P19835 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696059 | 0.94 | HTR3A (0.35) | HTR3AHRH4DAONOS1NOS2 | |
| SCHEMBL3155486 | 0.94 | — | — | |
| SCHEMBL1524762 | 0.91 | HTR3A (0.39) | HTR3AHRH4DAONOS1NOS2 | |
| SCHEMBL6585017 | 0.91 | HTR3A (0.39) | HTR3AHRH4DAONOS1NOS2 | |
| SCHEMBL15552104 | 0.91 | HTR3A (0.39) | HTR3AHRH4DAONOS1NOS2 | |
| SCHEMBL2334878 | 0.91 | HTR3A (0.39) | HTR3AHRH4DAONOS1NOS2 | |
| SCHEMBL1524741 | 0.91 | HTR3A (0.39) | HTR3AHRH4DAONOS1NOS2 | |
| SCHEMBL1057638 | 0.90 | — | — | |
| SCHEMBL2463395 | 0.88 | HTR3A (0.31) | HTR3AHRH4 | |
| SCHEMBL4983000 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004523599-A | — | — | 2004-08-05 | — | — | JP | claimed |
| EP-1353961-A2 | (CYCLOALKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS | ENGELHARD CORPORATION (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002016444-A2 | (CYCLOAKYL)METHYL SILANES AS EXTERNAL DONORS FOR POLYOLEFIN CATALYSTS | ENGELHARD CORPORATION (US) | 2002-02-28 | — | — | WO | claimed |