SCHEMBL669336

SCHEMBL669336

Oc1ccccc1-c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
HPGD P15428 4/20 0.48
HSD17B10 Q99714 4/20 0.48
BCL2L1 Q07817 1/20 0.48
MAPT P10636 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
ALOX15 P16050 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
LMNA P02545 2/20 0.43
NPC1 O15118 2/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP3A4 P08684 2/20 0.43
APEX1 P27695 2/20 0.43
RECQL P46063 2/20 0.43
BLM P54132 2/20 0.43
CA12 O43570 1/20 0.43
GMNN O75496 1/20 0.43
EGFR P00533 1/20 0.43
CA2 P00918 1/20 0.43
FYN P06241 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29203192 0.89 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL25419110 0.89 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL21951910 0.82 PGR (0.43) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL25223032 0.81 MEN1 (0.35) ALDH1A1MAPTSMN1; SMN2ALOX15TDP1
SCHEMBL7912181 0.81 HPGD (0.40) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL25424045 0.79 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL4226494 0.78 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL31589804 0.78 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL9463822 0.78 MAPT (0.43) ALDH1A1HPGDHSD17B10BCL2L1MAPT
SCHEMBL16355406 0.77 MAOA (0.36) ALDH1A1HPGDHSD17B10MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573634-B Pentafluorophenyl phosphonic acid di (pentafluorophenyl) ester flame retardant and preparation method thereof 长春市兆兴新材料技术有限责任公司 2024-04-26 CN claimed
CN-113278143-B Efficient unsaturated carbon dioxide-based polyol and preparation method thereof 中国科学院长春应用化学研究所 2022-12-20 CN claimed
CN-114702520-A Vanadium complex catalyst containing large steric hindrance phenol oxygen ligand and preparation method and application thereof 合肥工业大学 2022-07-05 CN claimed
CN-114573634-A Pentafluorophenylphosphonic acid di (pentafluorophenyl) ester flame retardant and preparation method thereof 长春市兆兴新材料技术有限责任公司 2022-06-03 CN claimed
CN-113278143-A Efficient unsaturated carbon dioxide-based polyol and preparation method thereof 中国科学院长春应用化学研究所 2021-08-20 CN claimed
CN-113387055-B Film, method for producing film, and bag 住友化学株式会社 2024-06-07 CN disclosed
CN-114573634-B Pentafluorophenyl phosphonic acid di (pentafluorophenyl) ester flame retardant and preparation method thereof 长春市兆兴新材料技术有限责任公司 2024-04-26 CN disclosed
CN-114573634-B Pentafluorophenyl phosphonic acid di (pentafluorophenyl) ester flame retardant and preparation method thereof 长春市兆兴新材料技术有限责任公司 2024-04-26 CN disclosed
CN-112724302-B Ethylene-alpha-olefin copolymer, process for producing the same, ethylene resin composition, and film 住友化学株式会社 2023-10-31 CN disclosed
WO-2023182498-A1 IONOMER CONTAINING METAL OF GROUP 2 OF PERIODIC TABLE 日本ポリエチレン株式会社 2023-09-28 WO disclosed
CN-112638997-B Film and packaging container 住友化学株式会社 2023-04-28 CN disclosed
CN-113278143-B Efficient unsaturated carbon dioxide-based polyol and preparation method thereof 中国科学院长春应用化学研究所 2022-12-20 CN disclosed
US-5721185-A REACTING GROUP 4 OR LANTHANIDE METAL CYCLOPENTADIENYL COMPLEX WITH LEWIS ACID THE DOW CHEMICAL COMPANY (US) 1998-02-24 US disclosed
EP-0641360-B1 PREPARATION OF ADDITION POLYMERIZATION CATALYSTS VIA LEWIS ACID MITIGATED METAL CENTER OXIDATION DOW CHEMICAL CO (US) 1997-10-01 EP disclosed
CN-1031578-C Homogeneous olfin polymerization catalyst by abstraction with borane DOW CHEMICAL CO (US) 1996-04-17 CN disclosed
EP-0520732-B1 Homogeneous olefin polymerization catalyst by ligand abstraction with lewis acids DOW CHEMICAL CO (US) 1995-12-06 EP disclosed
EP-0641360-A1 PREPARATION OF ADDITION POLYMERIZATION CATALYSTS VIA LEWIS ACID MITIGATED METAL CENTER OXIDATION. DOW CHEMICAL CO (US) 1995-03-08 EP disclosed
WO-1994021693-A1 PREPARATION OF ADDITION POLYMERIZATION CATALYSTS VIA LEWIS ACID MITIGATED METAL CENTER OXIDATION THE DOW CHEMICAL COMPANY (US) 1994-09-29 WO disclosed
US-5347024-A Preparation of addition polymerization catalysts via Lewis acid mitigated metal center oxidation THE DOW CHEMICAL COMPANY (US) 1994-09-13 US disclosed
EP-0520732-A1 Homogeneous olefin polymerization catalyst by ligand abstraction with lewis acids THE DOW CHEMICAL COMPANY (US) 1992-12-30 EP disclosed