Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727862 | 1.00 | LMNA (0.60) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL4490473 | 0.83 | LMNA (0.56) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL6423185 | 0.83 | LMNA (0.56) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL14722426 | 0.80 | RIPK1 (0.55) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL6424370 | 0.79 | LMNA (0.52) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL19090269 | 0.79 | LMNA (0.52) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL1496782 | 0.77 | LMNA (0.50) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL21830938 | 0.77 | AOC3 (0.53) | KDM4EAOC3 | |
| SCHEMBL2065089 | 0.76 | LMNA (0.48) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL2065742 | 0.76 | LMNA (0.48) | LMNAKDM4EL3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106269-A1 | METHOD FOR PRODUCING SUBSTITUTED SHIRAL DIOLS AND DIOL-ANALOGOUS DERIVATIVES | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2004-12-09 | — | — | WO | disclosed |