Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 9/20 | 0.36 |
| ▸ | CTSL | P07711 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686240 | 0.85 | CTSS (0.41) | CTSSCTSLUSP30CTSK | |
| SCHEMBL6693432 | 0.81 | CTSS (0.41) | CTSSCTSLUSP30CTSK | |
| SCHEMBL6686203 | 0.81 | BMP1 (0.42) | CTSSCTSLALDH1A1USP30CTSK | |
| SCHEMBL6690633 | 0.80 | USP30 (0.40) | CTSSCTSLUSP30CTSK | |
| SCHEMBL6690630 | 0.80 | USP30 (0.41) | CTSSCTSLUSP30CTSK | |
| SCHEMBL6693574 | 0.80 | CTSS (0.42) | CTSSCTSLUSP30CTSK | |
| SCHEMBL6688123 | 0.80 | CTSS (0.36) | CTSSCTSLCCR9USP30CTSK | |
| SCHEMBL6690766 | 0.79 | CTSS (0.44) | CTSSCTSLALDH1A1USP30CTSK | |
| SCHEMBL4800440 | 0.79 | CTSS (0.58) | CCKBRCTSSCTSLCTSK | |
| SCHEMBL4800453 | 0.79 | CTSS (0.58) | CCKBRCTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |