Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 10/20 | 0.41 |
| ▸ | CTSL | P07711 | 6/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690766 | 0.98 | CTSS (0.44) | BMP1CTSSCTSLCTSKALDH1A1 | |
| SCHEMBL6690633 | 0.93 | USP30 (0.40) | BMP1CTSSCTSLCTSKMMP1 | |
| SCHEMBL6686240 | 0.92 | CTSS (0.41) | CTSSCTSLCTSKUSP30 | |
| SCHEMBL6690347 | 0.91 | CTSS (0.45) | CTSSCTSLCTSKUSP30ADAMTS7 | |
| SCHEMBL6693574 | 0.91 | CTSS (0.42) | CTSSCTSLCTSKMMP1MMP2 | |
| SCHEMBL6690630 | 0.89 | USP30 (0.41) | CTSSCTSLCTSKMMP1MMP2 | |
| SCHEMBL6693432 | 0.86 | CTSS (0.41) | CTSSCTSLCTSKMMP1MMP2 | |
| SCHEMBL6690381 | 0.86 | CTSS (0.46) | CTSSCTSLCTSKMMP1MMP2 | |
| SCHEMBL6688123 | 0.84 | CTSS (0.36) | CTSSCTSLCTSKUSP30PLAU | |
| SCHEMBL6693396 | 0.81 | CCKBR (0.37) | CTSSCTSLCTSKALDH1A1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |