Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043208 | 0.75 | LMNA (0.70) | LMNAGPR84KMT2ACA12CA9 | |
| SCHEMBL4038858 | 0.75 | LMNA (0.54) | LMNAGPR84KMT2AMAPTCA12 | |
| Hydrochloric Acid SCHEMBL4045240 | 0.73 | LMNA (0.68) | LMNAGPR84KMT2ACA12CA9 | |
| SCHEMBL4213975 | 0.73 | LMNA (0.52) | LMNAGPR84KMT2AMAPTCA12 | |
| SCHEMBL11741524 | 0.71 | PDK2 (0.43) | LMNAKMT2ACA9KDM4EHPGD | |
| SCHEMBL14321593 | 0.71 | TP53 (0.58) | KMT2AMAPTKDM4EHPGDNPC1 | |
| SCHEMBL5953124 | 0.70 | DRD2 (0.40) | LMNAGPR84KMT2AMAPTCA12 | |
| Hydrochloric Acid SCHEMBL9056904 | 0.69 | DRD2 (0.40) | LMNAGPR84KMT2AMAPTCA12 | |
| SCHEMBL6689958 | 0.68 | LMNA (0.44) | LMNAGPR84CA12CA9DRD2 | |
| SCHEMBL5953253 | 0.66 | KMT2A (0.40) | GPR84KMT2AMAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039773-A2 | COUMPOUNDS MODULATING THE ACTIVITY OF GAPDH AND/OR IAMT | NORDIC BIOSCIENCE A/S (DK) | 2004-05-13 | — | — | WO | disclosed |