Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 11/20 | 0.82 |
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CDK1 | P06493 | 2/20 | 0.68 |
| ▸ | CDK4 | P11802 | 2/20 | 0.68 |
| ▸ | CDK2 | P24941 | 2/20 | 0.68 |
| ▸ | CDK7 | P50613 | 2/20 | 0.68 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.68 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680316 | 0.89 | AURKA (0.88) | AURKATP53MAPTL3MBTL1MEN1 | |
| SCHEMBL6692762 | 0.88 | AURKA (1.00) | AURKATP53MAPTL3MBTL1MEN1 | |
| SCHEMBL22095232 | 0.84 | AURKA (0.90) | AURKATP53MAPTMEN1KMT2A | |
| SCHEMBL15452613 | 0.83 | AURKA (0.79) | AURKATP53MAPTL3MBTL1MEN1 | |
| SCHEMBL22095087 | 0.81 | AURKA (0.84) | AURKATP53MAPTMEN1KMT2A | |
| SCHEMBL22095650 | 0.80 | AURKA (1.00) | AURKATP53MAPTMEN1KMT2A | |
| SCHEMBL6689634 | 0.80 | MAPK1 (0.63) | AURKATP53MAPTL3MBTL1MEN1 | |
| SCHEMBL22095269 | 0.79 | AURKA (1.00) | AURKATP53MAPTMEN1KMT2A | |
| SCHEMBL22095286 | 0.78 | KDM5B (0.95) | AURKATP53MAPTMEN1KMT2A | |
| SCHEMBL6677466 | 0.78 | MAPK1 (0.75) | TP53L3MBTL1MAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |