Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HCN1 | O60741 | 1/20 | 0.32 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.31 |
| ▸ | PDE1A | P54750 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692267 | 0.91 | LMNA (0.35) | HRH3ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6689067 | 0.88 | HRH3 (0.35) | HRH3ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6698686 | 0.87 | ABCB1 (0.40) | KMT2AMAPTLMNAHTR2CABCB1 | |
| SCHEMBL6693809 | 0.81 | HRH3 (0.38) | HRH3ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6688607 | 0.80 | ALDH1A1 (0.35) | HRH3ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6690893 | 0.78 | MAPT (0.33) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL6693776 | 0.77 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL6693175 | 0.76 | MAPT (0.32) | ALDH1A1MAPTHTT | |
| SCHEMBL6691800 | 0.75 | ABCB1 (0.40) | KMT2AMAPTLMNAHTR2CABCB1 | |
| SCHEMBL6692038 | 0.74 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0854168-B1 | Rubber composition | BRIDGESTONE CORP (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0948029-A2 | High pressure discharge lamp | NGK INSULATORS, LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |