Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119938 | 0.89 | PTGS2 (0.52) | PTGS2TUBB1LMNAMAPTERN1 | |
| SCHEMBL14231397 | 0.86 | TUBB1 (0.50) | PTGS2TUBB1LMNAMAPTERN1 | |
| SCHEMBL18400706 | 0.84 | TUBB1 (0.49) | PTGS2TUBB1LMNAMAPTERN1 | |
| SCHEMBL28721890 | 0.81 | ALDH1A1 (0.51) | PTGS2TUBB1LMNAMAPTERN1 | |
| SCHEMBL31130497 | 0.81 | ALDH1A1 (0.51) | PTGS2TUBB1LMNAMAPTERN1 | |
| SCHEMBL2919357 | 0.81 | PTGS2 (0.48) | PTGS2TUBB1LMNAMAPTERN1 | |
| SCHEMBL5644612 | 0.81 | LMNA (0.69) | LMNAMAPTERN1 | |
| SCHEMBL30374 | 0.80 | PTGS2 (1.00) | PTGS2TUBB1MAPTKDM4EHTR2A | |
| SCHEMBL13362321 | 0.78 | TUBB1 (0.44) | PTGS2TUBB1LMNAMAPTERN1 | |
| SCHEMBL13920937 | 0.77 | PTGS2 (0.57) | PTGS2TUBB1LMNAMAPTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656969-B2 | Polymer film, retardation film, polarizing plate, liquid crystal display, and compound | FUJIFILM CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9579332-B2 | Phosphonate analogs of HIV inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| EP-2606176-A1 | THERMAL TREATMENT | Aston University (GB) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012022949-A1 | THERMAL TREATMENT | ASTON UNIVERSITY (GB) | 2012-02-23 | — | — | WO | disclosed |